Abstract

Hyperpigmentary skin disorders may be defined as increased pigmentation of the skin and/or mucus membranes due to melanin pigment. Hyperpigmentation may be caused by abnormality in epidermis or dermis. Hyperpigmentary skin disorders may be broadly classified into two groups, epidermal which is characterized by ‘Brown hyperpigmentation’ and dermal which is known as ‘blue hyperpigmentation’ or ‘Ceruloderma.’ Pigmented lesions can be close mimickers of melanoma and clinically challenging to diagnose. These can be melanocytic or non-melanocytic pigmented disorders. Pigmented lesions are closemimickers of melanoma and histopathology is a cornerstone for diagnosing these lesions. Pigmented skin lesions comprise a large component of most histopathologists’ workload, and although there is a wide spectrum of histological appearances most can be reported as simple benign naevi. Histopathological examination in several studies revealed epidermal pigmentation as the commonest finding followed by dermal pigmentation with or without hyperkeratosis

Description