Journal of Cardiovascular Disease Research
A STUDY ON PERIPHERAL LYMPHADENOPATHY SUSPICIOUS FOR TUBERCULOSIS BY CYTOMORPHOLOGY, AFB POSITIVITY AND CBNAAT IN SOUTH ODISHA
Dr Vattikulla Rajesh , Dr Sanjeeb kumar pradhan , Jyothis Joy George , Dr Abhilash Panda
JCDR. 2023: 396-403
Abstract
AIM AND OBJECTIVE: Correlation of cytomorphological pattern and AFB positivity of FNAC based cytosmears with CBNAAT result from all lymphadenitis suspicious of TB lesion. PATIENTS AND METHODS: This is a comparative study conducted in Department of Surgery in collaboration with Department of Pathology M.K.C.G. M.C.H., Berhampur from September 2021 to January 2023. Out of total of 398 cases, 354 cases were included in the study in which cytomorphology of aspirated material were correlated with AFB stain positivity and CBNAAT from lymph nodes suspicious for tuberculosis. RESULTS: The cytological diagnosis made most frequently was granulomatous lymphadenitis (64%), followed by caseating granulomatous lymphadenitis (14%), reactive lymphadenitis and suppurative lymphadenitis (11% each). The presence of acid-fast bacilli by ZN staining was seen in 17 samples (5%). 88 samples (25%) were positive in CBNAAT. CBNAAT positivity was seen in 36 cases (72%) of caseating granuloma, 46 cases (20%) of granulomatous lesions and 6 (15.3%) suppurative lymphadenitis cases; all cases diagnosed as RHL were negative. Out of the total 88 patients 3 patients (4%) were Rifampicin resistant, one case each belonging to cervical, axillary and inguinal lymph nodes
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