Abstract

Background: Acute coronary syndrome (ACS) is a leading cause of morbidity and mortality worldwide. Early detection is crucial for reducing cardiac damage in people with ACS. Prompt risk classification and diagnosis allows for early therapy commencement, reducing the patient's chance of unfavourable outcomes. Cardiac troponins I and T, which have high sensitivity and tissue specificity, are often used to diagnose ACS alongside an electrocardiogram (1). Objectives: 1. Study the analytical competence of PAPP-A in patients admitted to the emergency department with chest pain and finally diagnosed as ACS. 2. Comparison of PAPP-A levels in sub-types of ACS. 3. Comparison of PAPP A and troponin I in subtypes of ACS. Material & Methods: Study Design: Case control study. Study area: The study was conducted in the Department of General Medicine, in a tertiary Care teaching hospital. Study Period: October 2022 to September 2023. Sample Size: A case-control study of 88 subjects divided equally into 2 groups.

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