Abstract

The combined costs of direct medical care and time away from work due to chronic rhinosinusitis and sinonasal polyposis are substantial. Inflammation is central to the pathophysiology of Chronic Rhinosinusitis, and a wide range of medication, including topical corticosteroids, antibiotics, saline irrigations, and systemic steroids, is available to treat it with surgery being done in cases not responding to maximal medical therapy. Material and Methods: This study was conducted at the Department of ENT at GSL Medical College and General Hospital, Rajamahendravaram, and Nimra Institute of Medical Sciences, Vijayawada, Andhra Pradesh, India between, January 2022 to May 2023. In this study, forty patients with Chronic Rhinosinusitis with Sinonasal Polyposis(CRSwP)are analyzed. In this study, pre and post operative systemic steroids were administered to 20 patients, while the other 20 received placebos. Critical data analysis was performed on operative and clinical information. Results: This investigation is a double-blind, placebo-controlled trial assessing the effectiveness of pre- and post-operative systemic steroids in improving surgical outcomes for patients undergoing ESS for the treatment of CRSwP. We employed subjective and objective indicators of success. The major purpose of the research was to determine how steroid use affected these measures of subjective and objective well-being. Conclusion: Finally, adjuvant steroids, which are given, provide a better symptom relief and can help prevent postoperative issues such as scarring, synechiae formation, postoperative crusting, and recurrence as well

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