Abstract

Diabetes mellitus (DM) refers to a group of common metabolic disorders that share the phenotype of hyperglycaemia. Diabetes is considered a lifestyle disease and diet plays an important role in the development of DM and its associated complications. It is claimed that there is an inverse relationship between Mg intake and incidence of diabetes mellitus (DM)2. Mg deficiency is common in diabetic patients. Magnesium deficiency may lead to decreased synthesis of glutathione thereby enhancing the process of lipid peroxidation. The free radical mediated lipid peroxidation (oxidative stress) has also been implicated in the pathogenesis of diabetes mellitus. Methodology- The study was conducted on 70 patients of type 2 diabetes mellitus admitted to GIMS, Kalaburagi between January 2020 and December 2021. Also 70 non diabetic patients admitted during the same period were included in the study under the control group. Patients were considered to be diabetic based on WHO criteria for diagnosis of diabetes mellitus. All the necessary investigations were done. Estimation of serum magnesium was done and the results were interpreted. Results- The mean serum magnesium was 1.65 mg/dl and 1.99 mg/dl in diabetics and control respectively. The mean serum magnesium level in patients on OHA was 1.99 mg/dl on insulin was 1.59 mg/dl and in patients on both OHA and insulin was 1.26 mg/dl. The serum magnesium in patients who had diabetes under control was 1.75 mg/dl and that in whom it was uncontrolled was 1.23 mg/dl. Conclusion- Hypomagnesemia is a factor in type 2 diabetes mellitus patients leading to various complications. Hence, it is worthwhile estimating magnesium levels in type 2 diabetes mellitus patients and probably correlates their relationship with various complications.

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