ISSN 0975-3583

Journal of Cardiovascular Disease Research

    A study to evaluate the magnetic resonance imaging characteristics of epileptogenic substrates

    Rahul Mangal, Puneet Kumar Awasthi, Megha Tripathi, Navjeet Kaur
    JCDR. 2023: 2158-2164


    The present study is to review the efficacy of magnetic resonance imaging in the evaluation of patients with seizures. Material and methods- The study was conducted on patients with magnetic resonance imaging reference for seizures in the Department of Radio diagnosis, Dr. S. N. MEDICAL COLLEGE and associated group of hospitals, JODHPUR. Imaging was done with ACHIEVA 1.5 TESLA MAGNETIC RESONANCE IMAGING equipment from PHILIPS Results- Majority of patients who presented with seizures belonged to the first three decades of life with male preponderance. The proportion of patients presenting with partial seizures were higher than those with generalized seizures. The typical magnetic resonance signal intensity characteristics of epileptogenic substrates can be used to identify as well as diagnose the lesions specifically. Abnormalities were identified in 60 percent of the study population while 40 percent had normal magnetic resonance imaging. Mesial temporal sclerosis was the most commonly identified substrate in patients presenting with refractory partial seizures, followed by gliosis, which was followed by infections, tumours, developmental anomalies and vascular malformations in that order. The diagnostic yield from magnetic resonance imaging is high in patients with refractory partial seizures. Conclusion-Magnetic resonance imaging should be considered in the initial evaluation of patients presenting with seizures, particularly with intractable partial seizures because of its high sensitivity for epileptogenic substrates, superior soft tissue contrast, multiplanar capability, lack of beam hardening artifact and lack of ionizing radiation



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    Volume & Issue

    Volume 14 Issue 2