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Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    A study to measure and compare the effectiveness of intravenous magnesium sulphate and intravenous esmolol in attenuation of blood pressure response to laryngoscopy and intubation


    Dr. Meghana Badari Narayan, Dr. Mohan Kumar Ramiah Mahadeva, Dr. Geethashree B, Dr. Sagarika UL
    JCDR. 2024: 3867-3874

    Abstract

    Attenuation of intubation response has been practiced by various methods and using drugs, topically or systemically. This study was undertaken to compare the effectiveness of magnesium sulphate and esmolol for attenuation of blood pressure response to laryngoscopy and intubation. Following ethical committee approval, patients fulfilling the essential criteria were selected. Patients were randomized and either received 0.5mg/kg esmolol or 30mg/kg magnesium sulphate intravenously and vital parameters were recorded. SBP and DBP in esmolol group showed statistically significant decrease from 1st to 10th minute after intubation from baseline. MAP in esmolol group showed statistically significant increase from baseline at intubation and decrease from 2nd to 10th minute after intubation from baseline.

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    Volume 15 Issue 6

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