Abstract

Lipids have a key role in the maintenance of cell integrity. Hypolipidemia is related with increased risk of cancer and mortality. Lipids might be associated with cancers because they are important constituent of cell membrane. The aim of this study is to study the lipid profile in Breast cancer patients and to find out any correlation with histopathological grading and staging. Material and method: Present study was undertaken in 70 histopathologically confirmed breast cancer patients in Department of Pathology Gandhi Medical College Bhopal, after taking informed written consent and ethical clearance. Lipid Profile were estimated and compared with age and sex matched healthy controls. Statistical analysis was done using chi square test. Result: Total cholesterol and triglycerides were raised in cancer patients as compared to controls and this difference was statistically significant (p-value<0.05). Mean values of LDLC and VLDLC were also raised but not significant with p value>0.05. Hence it is concluded that total cholesterol and triglycerides are highly elevated in breast cancer patients. However, no correlation of altered lipid profile seen in grading and staging of Breast cancer

Description