Abstract

The aim of the study is comparing the effects of intraperitoneal ropivacaine and bupivacaine for postoperative pain relief in laparoscopic surgeries. 60 Patients were divided into two groups. In a sequential manner i.e. 1st patient will be allocated to group I, 2nd patient will be allocated to group II, 3rd patient will again be allocated to group I, so on and so forth till each group has 30 patients each. Results: The mean duration of surgery in the ropivacaine group was 126.67 ± 43.89 minutes and in the bupivacaine group it was 107.63 ± 41.03 minutes. The difference was found to be statistically not significant (P<0.05), showing a comparable duration of surgery between the two groups. The comparison of mean VAS between the two groups at different time intervals were assessed. In the ropivacaine group, the mean VAS at 1st hour was 1.70 ± 0.75. The mean VAS score showed a continuous increase till 12th hour and then a slight fall at the end of the study at 24th hour. In the bupivacaine group, the mean VAS at 1st hour was 0.67 ± 0.61. The mean VAS score showed a continuous increase till 8th hour then a fall at 12th hour, this fall continued till the end of the study at 24th hour. The difference of mean VAS between the two groups at different time intervals was calculated using unpaired t test. The mean VAS score was higher in the ropivacaine group at 1st hour, 2nd hour in comparison to the bupivacaine group (P<0.05), while it was comparable at 4th hour, 6th hour and 12th hour (P>0.05). At 8th hour the mean VAS in the ropivacaine group was significantly lower in comparison to the bupivacaine group (P<0.05), while at 24th hour the mean VAS in the ropivacaine group was significantly higher in comparison to the bupivacaine group (P<0.05). Conclusion: Intraperitoneal instillation of Bupivacaine 0.25% (not exceeding 2 mg/kg), and Ropivacaine 0.2% 30 ml is an effective method of postoperative pain relief in laparoscopic surgeries. Both the drug significantly reduces postoperative pain. We found that instillation of local anesthetic agents intraperitoneally is easy and effective technique to attenuate postoperative pain provide profound analgesia for prolonged period thus requiring less rescue analgesia.

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