ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    Analysis of lipoprotein (a) levels in patients with acute coronary syndrome: A comparison of type 2 diabetes and non-diabetics


    Dr. Shazan Mohiuddin, Dr. Mohammed Mudassir Jaweed, Dr. Shaik Gazi Moin Ahmed, Dr. Majaazuddin Mohammed, Dr. Syed Huzaifa Quadri
    JCDR. 2023: 1016-1020

    Abstract

    There has been a substantial rise in the incidence of cardiovascular disease in recent decades. Coronary artery disease (CAD) may have a genetic or environmental origin, or the two may be related. Material and Methods: Using demographic and sex matching, from the total 88 patients, 44 patients with type 2 diabetes and 44 are the non-diabetic were selected from hospitalized patients with acute coronary syndrome. The patients' lipoprotein (a) levels were analyzed. Patients hospitalized with acute coronary syndrome to the cardiac ICU at the Gandhi Hospital, during the study period July 2022 to November 2022. Results: Heart disease is the major cause of death among those who have diabetes mellitus. According to the Framingham Heart Study, those with diabetes had a 1-5 times higher risk of coronary artery disease, acute myocardial infarction, and sudden death. Therefore, the prognosis for diabetic individuals with CAD is worse than that of people without diabetes. There are a number of complications that can arise in patients with diabetes, including early thrombus formation, smooth muscle proliferation, endothelial dysfunction, and platelet dysfunction. Conclusion: Lp(a) levels are greater in patients with type 2 diabetes during acute coronary syndrome compared to patients without diabetes. Compared to the general population, patients with type 2 diabetes are about twice as likely to have abnormally high levels of Lp(a).

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    Volume & Issue

    Volume 14 Issue 5

    Keywords

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