Journal of Cardiovascular Disease Research
Analysis of the role of E-cadherin and cytokeratin 5/6 in sub classification of breast cancer
1Dr. Kandanala Mallika, 2Dr. Pujari Lahari, 3Dr. Anin
JCDR. 2023: 1620-1629
Abstract
Different cytokeratins are expressed in different epithelial types and at different stages of differentiation. Consequently, different epithelial types have different specific cytokeratin expression profiles, which usually remain constant after neoplastic transformation. E-cadherin is a transmembrane glycoprotein that mediates a cell–cell adhesion in the epithelial tissues.
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