Abstract

This research was conducted on patients afflicted with diabetic foot ulcer (DFU) in order to evaluate the clinical attributes, range of microbial populations, antibiotic susceptibility, and establish an empirical approach for antimicrobial treatment. Materials & methods: Clinical information, tissue and and pus collections were gathered from a total of 50 patients diagnosed with diabetic foot ulcer. These samples were handled in accordance with the guidelines set forth by the Clinical and Laboratory Standards Institute. Both the clinical and microbiological data were analyzed. Results: This study of 50 diabetic foot ulcer patients revealed a male predominance. Most patients were in 50-60 years age group. Among the samples, Gram-positive organisms accounted for 29.48%. Staphylococcus aureus (17.95%) showed sensitivity to amikacin, Linezolid (100%), and Vancomycin (100%). Conclusion: In DFU, Gram-positive bacteria displayed varying degrees of resistance to commonly utilized antibiotics, while exhibiting sensitivity to aminoglycosides. Based on these results, Amikacin and Gentamicin are potential options for empiric antibiotic treatment in DFU infections.

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