Abstract

Guillain-Barré syndrome (GBS) is a very rare immune mediated disorder which is associated with demyelination of peripheral nervous system and progressive muscle weakness that occurs mostly in previously healthy individuals. It usually presents with ascending paralysis and is severe enough to warrant hospital admission for its management. Methodology: The current study is a retrospective, observational study was conducted for the assessment of clinical profile data and treatment pattern of Guillain-Barré syndrome. Result: According to our data, we observe that treatment like IVIG, Plasmapheresis, Nutrition therapy; Analgesic etc. are the common medication prescribed by the physicians as per patient condition. AIDP is the most common sub-type of GBS was observed in patients, with about 60% AIDP, 20%AMAN, 20% MFS patients were observed. The mostly observed symptoms in the GBS are weakness of limbs, bifacial weakness, slurring of speech and fever. As per our data about 72% of males and 28% of females were diagnosed with GBS. Conclusion: Both IVIG and Plasmapheresis treatment showed significant improvement within our study setting IVIG was the preferred treatment option due to low side effect profile and ease of administration however cost of treatment is higher compared to Plasmapheresis.

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