ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    Assessment of D-dimer levels in stroke patients


    Dr. Deepak Goyal, Dr. Parag Sharma, Dr. Amit Sharma
    JCDR. 2023: 3783-3787

    Abstract

    Long term complications and adverse effects associated with stroke are one of the important leading causes of mortality and morbidity in the world as well as in India. The present study was conducted to assess D-dimer levels in stroke patients. Materials & Methods:100 patients of stroke were selected. Detailed history regarding smoking, alcoholism etc. were taken.Venous sampling for quantitative measurement of D-dimer was taken at the time of admission. Values less than 500ng/ml was considered normal and values equal or more than 500ng/ml were taken as raised D-dimer level.Stroke severity was assessed on admission using the National Institutes of Health Stroke Scale. Results: Out of 87 cases of raised D-dimer level, most of the patients were in age group of 51-60 years with 35.63% (35) followed by 41-50 years with 31.03% (27). There was a positive correlation between the age and D-dimer was seen (p=0.004). Out of 5 patients with normal D-dimer, 38.46% were smokers and with raised D- dimer level 73.5% were smokers. Out of 13 patients with normal D-dimer, 7.69% (1) were alcoholic and 92.3% (12) were non-alcoholic, and out of 87 patients with raised D-dimer, 19.54% (17) were alcoholic and 80.46% (70) were non-alcoholic. Out of the 87 patients who presented with raised levels of D-dimer 42.53% (37) reported with severe stroke with NIHSS score 21-42 followed by 29.88% (26) with moderate to severe stroke with NIHSS score 16-20, and 25.28% (22) had score in the range of 5-15 that is moderate score. In this study NIHSS score was higher with raised level of D-dimer. There was a significant correlation of NIHSS score with D-dimer level (p value<0.0001). Conclusion: D-dimer values in stroke constitutes an important parameter in the evaluation of stroke specially its severity.

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    Volume & Issue

    Volume 14 Issue 1

    Keywords