Abstract

Thyroid disorders are highly prevalent conditions worldwide, posing significant implications for maintaining optimal thyroid hormone levels, which play a crucial role in normal reproductive function. The incidence of thyroid disorders tends to increase with age, and women often experience symptoms related to their menstrual cycles, rendering them more susceptible to developing thyroid dysfunction. The primary objective of this study was to compare the thyroid profile between premenopausal and postmenopausal women. Materials and Methods: A total of 95 premenopausal women (aged over 40 years) and 100 postmenopausal women (within a menopause duration of up to 5 years) were selected as participants for this study. Thyroid profile assessment was performed on all subjects under standardized conditions, ensuring that the assessments were conducted in a basal-fasting state. Results: Analysis of the results revealed that the mean levels of thyroid-stimulating hormone (TSH), FT3, and FT4 were higher in postmenopausal women. Similarly, the mean levels of [insert specific hormone(s)] were slightly elevated in the postmenopausal group. However, it is important to note that no statistically significant differences were observed in the thyroid hormone profile between the premenopausal and postmenopausal groups. Conclusion: Although the present study did not yield statistically significant differences in the thyroid profile between premenopausal and postmenopausal women, it is imperative to emphasize the necessity for further research with a larger sample size within the Indian population. This would allow for a more comprehensive evaluation of the association between the thyroid profile and the premenopausal and postmenopausal statuses.

Description