Abstract

Aim and objectives: The aim of this research was to compare conventional procedures of diagnosis & treatment of newborn sepsis with an evaluation of platelet indicators. Materials and method: The study was done in NICU division of Department of Paediatrics in TMMC & RC, Moradabad. All neonates admitted in the neonatal intensive care unit with clinical diagnosis of neonatal sepsis were included for entire study duration. The cases were all neonates with culture positive sepsis or clinical sepsis symptomatic babies with positive septic screen. The controls were all neonates suspected of having sepsis but had negative blood culture, negative sepsis screen & whose antibiotics was then stopped. Results: Neonatal sepsis was found more among subjects with late onset sepsis (55.26%) as compared to early onset sepsis (44.74%).Neonatal sepsis was found more among subjects delivered vaginally (81.03 %) as compared to subjects delivered LSCS (11.29%). The average platelet count was inferior in cases (sepsis screen positive & blood culture positive) group than in the control cluster. The average MPV was significantly high in the case cluster than in the control cluster. Conclusion: Thus, it may be concluded that platelet indices are readily available, inexpensive and sensitive markers to diagnose septic babies and when integrated with traditional sepsis screen help to specifically make the diagnosis of neonatal sepsis.

Description

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