ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    Assessment of platelet indices in patients with acute coronary syndrome in tertiary care center in central India: A cross-sectional study


    Archana Aher, Nazia Bhatti, Suvidha Fulzele
    JCDR. 2023: 1891-1899

    Abstract

    Acute coronary syndrome (ACS) refers to a group of conditions due to decreased blood flow in the coronary arteries such that part of the heart muscle is unable to function properly or dies and that is a consequence of platelet rich coronary thrombus formation.Objective:Assessment of platelet indices in patients with ACS in tertiary care centre, also to assess platelet indices to predict in hospital outcome. Methods: This is a prospective, cross-sectional study which was conducted in ICU of Medicine department in a tertiary care hospital and Medical College situated in the central India. Results: Majority of the patients had platelet indices in normal range i.e., PC (66.67%), MPV (54.17%), PDW (76.04%), PCT (82.29%), P-LCR (64.58%)and P-LCC (58.33%). Some of the patients had reduced platelet indices i.e. PC (33.33%), MPV (7.29%), PDW (11.46%)and PCT (4.17%). Some of the patients had raised platelet indices i.e.MPV (38.54%), PDW (12.50%), PCT (13.54%), P-LCR (35.42%)and P-LCC (41.67%). Majority of the patients had STEMI (72.92%) followed by UA (19.79%), and NSTEMI (7.29%). There was no significant association in type of ACS (STEMI, NSTEMI, and UA) with any of the platelet indices (all p-values > 0.05).There was no significant association between outcomes and any of the platelet indices (all p-values > 0.05). Conclusion:Platelet indices are not significantly associated with ACS and in-hospital mortality . However, further studies with large sample size are required to confirm the findings of the present study.

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    Volume & Issue

    Volume 14 Issue 4

    Keywords