Abstract

The simplest, cost-effective, and relatively recent classification of cirrhosis is based on the serum albumin and total bilirubin, the albumin-bilirubin score (ALBI score) which has been found to not only characterize the stage of cirrhosis but can also predict the prognosis with high degree of sensitivity and specificity. As ALBI utilizes two common, easily available, repeatable, and cost-effective blood tests,it is the most preferred and reliable, prognostic score for estimating the mortality rates in patients with last stage of cirrhosis. The aim of this study is to assess of the severity of decompensated liver cirrhosis using albumin-bilirubin (ALBI) score. Material and Methods: Inclusion Criteria is Patients >18 years of age and both sex with decompensated liver cirrhosis (known or newly detected) irrespective of etiology. Exclusion Criteria are Patients with acute liver failure, Patients with coexisting chronic kidney disease, Patients with overt proteinuria, Patients being treated for acute infectious disease. Results: A total of 100 participants were taken in our study, out of which 74 (74%) were male and 26 (26%) were female. A majority of patients belong to 41-50 yrs group (39%). A total number of 93 (93%) participants did not require oxygen support and the remaining 7 (7%) participants were on oxygen support. Among participants with grade 1 hepatic encephalopathy 8 out of 10 belong (71.4%) to grade 3 ALBI, 11 of 11 (100%) participants from grade 2 hepatic encephalopathy belonged to grade 3 ALBI score, 15 out of 18 (83%) grade 3 HE belongs to ALBI grade 3, 3 out of 5 (60%) from grade 4 HE belongs to ALBI grade 3. The mean albumin in survived patient was 2.48 with standard deviation of 0.49 & in expired patient it mean was 2.58 with standard deviation of 0.63 with p value of 0.415. In Survived patient mean INR was 1.80 with standard deviation of 0.72 & in expired patient mean was 2.27 with standard deviation of 1.12 p value being 0.014. Conclusion: Albumin-bilirubin score (ALBI score) is a recently developed score that utilizes the total serum albumin and bilirubin to generate the scores utilized for staging the disease. It has been described to be safe, simple, costeffective, reliable, reproducible, and repeatable score for staging the severity of cirrhosis as well as predicting the mortality

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