Abstract

The objectives of this study were to study the electrocardiogram (ECG) changes in a group of newly diagnosed subclinical hypothyroid females and to compare the ECG changes in subclinical hypothyroid females with normal healthy euthyroid individuals. Material & Methods: This study was conducted in the Department of Physiology. We studied 30 patients with newly diagnosed and untreated primary SCH, outpatient department (with non-specific complaints such as fatigue, mild weight gain, dry skin, and depressive feelings but without overt symptoms and signs of thyroid hormone deficiency. Results: A total of 60 subjects (30 in the study group and 30 in the control group) were included in the study. TSH levels were significantly higher in SCH patients than controls, but fT4 and fT3 were comparable. Conclusion: ECG changes in SCH showed increase in the QTc interval as compared to controls, which predisposes to the potentially life-threatening ventricular arrhythmias. However, the other parameters of ECG such as QRS interval, PR interval, and QRS axis were similar to the controls

Description