Abstract

Between 30% and 92 percent of people are affected. After the suction drain is removed, it is common for the seroma to reappear, necessitating repeated skin punctures. This results in a higher risk of infection, as well as a delay in adjuvant therapy of several weeks. Objectives: Assessment of the Total volume of the Seroma aspirated and Early Drain removal. Method: The study was conducted on a total of 62 patients undergoing Modified Radical Mastectomy at KARNATAKA INSTITUTE OF MEDICAL SCIENCES, HUBLI from December 2019 to January 2022. In the study period, 62 patients fulfilled the inclusion criteria and were randomized, 31 in the methylprednisolone intervention group and 31 in the control group. Results: The age of the subjects varied from 25 years to 75 years. The average age cases of carcinoma breast were >45 years. Out of 62 patients, 7 patients (22.6%) in the test group had seroma, and 11 patients (35.5%) in the control group had seroma which was statistically insignificant.There is a significant difference in the drain removal days between the test and control groups. The post-operative drain removal within 5 days in the test group is 77.4% compared to the control group 16.1%. Conclusion: Various factors implicated to be predisposing factors for seroma formation such as the age of the patient, BMI of the patient, stage of the tumour, the role of neoadjuvant therapy, number of lymph nodes dissected, lymph node ratio, stage of the tumour, total drain output, drain removal day and molecular subtype were analyzed and age of the patient >45yrs, BMI>25, were found have a statistically significant association with seroma formation. The total volume of seroma aspirated was lower in the test group. Test group also favours the early drain removal and reduced drain output.

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