Abstract

Background: This cross-sectional study aimed to investigate the association between carotid artery intima-media thickness (CIMT) and risk factors for cardiovascular disease (CVD). Methods: The study included 250 participants aged 40-70 years old who underwent CIMT measurements using high-resolution ultrasound. The participants' medical history and risk factors for CVD, including age, gender, smoking status, hypertension, dyslipidemia, and diabetes, were assessed. Multiple regression analysis was used to evaluate the association between CIMT and each risk factor. Results: The mean CIMT was 0.81 ± 0.18 mm. Hypertension (β=0.28, P<0.001), dyslipidemia (β=0.18, P=0.03), and diabetes (β=0.21, P=0.01) were significantly associated with increased CIMT after adjusting for age, gender, and smoking status. Age and gender were also significantly associated with CIMT (β=0.39, P<0.001 and β=-0.23, P=0.002, respectively). Conclusion: The results of this study demonstrate a significant association between CIMT and hypertension, dyslipidemia, and diabetes, independent of age, gender, and smoking status. These findings suggest that CIMT measurement may be a useful tool for identifying individuals at high risk of CVD and may help to inform clinical decision-making for the prevention and management of CVD.

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