ISSN 0975-3583
 

Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    ASSOCIATION BETWEEN PLATELET-TO-LYMPHOCYTE RATIO, NEUTROPHIL-TO-LYMPHOCYTE RATIO, MONOCYTE-TO-HDL CHOLESTEROL RATIO AND LIPID PROFILE PARAMETERS IN SEPSIS - A PROSPECTIVE OBSERVATIONAL STUDY


    Jeyakumar Manavalan, Viveka Murugiah, Augustiya Natarajan, Afrah Abdul Malick, Manikandan Bose
    JCDR. 2024: 1051-1060

    Abstract

    Background: Sepsis is a global health issue and a medical emergency that requires timely intervention. Early diagnosis and prediction of severity are very essential to reduce the mortality in sepsis. Neutrophil-Lymphocyte Ratio (NLR), Platelet-Lymphocyte Ratio (PLR) and Monocyte-HDL Ratio (MHR) can be easily calculated from the Complete Blood Count (CBC) values and lipid profile and are relatively less expensive which can be used to predict the outcome of sepsis. We aimed to study the association between these parameters and the clinical outcomes of patients with sepsis. Methodology: We have conducted a prospective observational study including 80 study participants from medical and surgical ICUs. Among them, 59 survived and 21 patients expired. Neutrophil-Lymphocyte Ratio (NLR), Platelet-Lymphocyte Ratio (PLR) and Monocyte-to-HDL Ratio (MHR) were calculated. SOFA score was also calculated at two intervals one during admission and on day 5. All the parameters were compared between the survivors and the non-survivors.

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    Volume 15 Issue 4

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