Abstract

Maternal dyslipidemia experts potential and adverse impacts on pregnant women and newborns. However, the association between maternal serum triglycerides level and the risk of macrosomia has not yet been clearly studied.We did this study for association between the maternal serum triglycerides level and risk of macrosomia among the non-diabetic and non obese pregnant women. OBJECTIVE: To find the associations of maternal triglyceride levels with neonatal macrosomia in non-obese and pregnant women without Diabetes Mellitus . SETTING: SCB Medical College, Cuttack, Odisha, India. MATERIAL AND METHOD: This was a escriptive cross-sectional study of 100 pregnant patients with BMI less than 30. The medical records of 100 non obese and non-diabetic pregnant women at term were prospectively analyzed. Maternal fasting serum triglyceride levels were measured during late pregnancy. Scatter diagram was used to analyze the variables associated with the risk of macrosomia.RESULTS:Maternal TG level was higher in patient with macrosomia babies (333.00 ± 51.62) compare to those without macrosomia (253.15 ± 81.02). This difference in mean was statistically significant (P value = 0.001) (Table 5). There was a positive correlation between birth weight and maternal triglyceride level which was statistically significant with correlation coefficient value of 0.278 (r) and p value of 0.005. CONCLUSION:Our findings highlight the importance of maternal lipid metabolism in fetal overgrowth and may have implications for the etiology and primary prevention of macrosomia. However, further prospective investigations involving larger population and basic research studies are necessary to fully evaluate their clinical value and the mechanisms

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