Abstract

Thyroid disorders are considered the most common endocrine disorders affecting 5-10% of individuals. Vitamin D is an important bio-molecule that plays a role in the signaling pathways related to immune modulation and oxidative stress. Vitamin D receptor (VDR) gene polymorphisms were found to be associated with the risk for Graves' disease. As thyroid hormones are essential for normal organ growth, development function the basal metabolic rate of all cells, its alteration can affect the entire metabolism and can alter the activity of serum enzymes like LDH. There is negotiation regarding the increased/decreased levels of LDH in thyroid disorders with some studies stating that LDH can be used as a parameter for screening the thyroid disorder. But some contraindicated results prevail in this area of research. To clear some air an attempt was made on one study group to analyse the levels of LDH and Vitamin D in hyperthyroidism disorder and to find out correlation (if any) that exists between LDH and thyroid hormone

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