Abstract

Introduction: In diabetes, role of vitamin D in insulin sensitivity and its protective effect from complications has been proven by many animal model studies. However, place of vitamin D as a preventive or therapeutic measure in diabetes mellitus is yet not established. Aim: To study the association between vitamin D level and micro vascular complications of diabetes mellitus. Methods: A hospital based observational study on 119 Patients of type 2 diabetes mellitus at a tertiary care center India was done between Jan 2020 to Dec 2022. All routine lab parameters were done and patients were evaluated for diabetic retinopathy and neuropathy and nephropathy. Statistical analysis was done by pearson correlation test, fisher’s exact test and ANOVA. Linear regression analysis was also done. Results: out of 119 patients, with mean age of 49.5 year, mean duration of diabetes 6.5yr. On comparison between vitamin D level and frequency of diabetic neuropathy, significant association was found whereas no significant association was found between vitamin D deficiency and diabetic nephropathy and retinopathy. Conclusion: Vitamin D deficiency may be a risk factor for development of diabetic neuropathy and dyslipidaemia, in patients with type 2 diabetes mellitus.

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