Abstract

Atrial myxoma is the most common benign primary cardiac neoplasm.Myxomas can arise in any of the cardiac chambers although 75% occur in left atrium.Clinical presentation mimics multiple cardiac diseases. Material and Methods During the 2017–2023 study period, eleven cases of cardiac myxomas at the Cardiac Surgery Department were chosen for study. Microsoft Windows SPSS software was used to analyze the data. Results Out of 11 cases of cardiac myxomas 9 were females (81%).Median age is 58 yrs (Range 34-68yrs).Most common site was left atrium(63%).Majority of patients presented with non specific cardiac symptoms such as breathlessness, unstable angina and generalized tiredness. Echocardiography could establish pre resection diagnosis in all cases. Gross examination of specimen showed tumor diameter ranged from 2.5-7.5 cm. Histopathological diagnosis was based on characteristic spindle or stellate cells with eosinophilic cytoplasm and ovoid nucleus, embedded in amorphous myxoid matrix. All cases showed hemosiderin laden macrophages in background. Gamnagandy bodies were noted in 2 cases (18%)and calcification was noted in one case. Conclusion The present case review showed the clinical and pathological profiles of cardiac myxomas. Inflammatory cells and hemosiderin deposits were common findings. Longterm follow up is excellent with no surgical recurrences noted in 11 cases.

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