Abstract

Urinary tract infection (UTI) is one of the most common bacterial infections encountered in clinical practice. It can range from uncomplicated cystitis to pyelonephritis, and may result in serious complications if not treated promptly. The incidence of UTI is high in females as compared to males. Objective: The objective of this study was to determine the bacterial profile and their antibiotic susceptibility pattern in clinically diagnosed UTIs.Methods: This was a retrospective study conducted in a tertiary care hospital over a period of one year. The study included all patients with clinically diagnosed UTIs who underwent urine culture and sensitivity testing.The data collected from the medical records included age, gender, urine culture report, and antibiotic sensitivity pattern.Results: A total of 750 urine culture reports were analyzed. The majority of the patients were females (n=600, 80%). Escherichia coli was the most common organism isolated (n=500, 66.7%), followed by Klebsiella spp. (n=100, 13.3%), Proteus spp. (n=70, 9.3%), and Pseudomonas aeruginosa (n=50, 6.7%). The antibiotic susceptibility pattern of Escherichia coli showed high sensitivity to nitrofurantoin (90%), amikacin (87%), and ceftriaxone (80%), while it was highly resistant to ampicillin (92%) and cotrimoxazole (85%). Klebsiella spp. showed high sensitivity to amikacin (87%) and ceftriaxone (80%), while it was highly resistant to ampicillin (92%) and cotrimoxazole (90%). Proteus spp. showed high sensitivity to ceftriaxone (87%) and amikacin (80%), while it was highly resistant to ampicillin (97%) and cotrimoxazole (90%). Pseudomonas aeruginosa showed high sensitivity to amikacin (80%) and ceftriaxone (70%), while it was highly resistant to ampicillin (98%) and cotrimoxazole (90%).Conclusion: Escherichia coli was the most common organism isolated in clinically diagnosed UTIs. The antibiotic susceptibility pattern showed that nitrofurantoin, amikacin, and ceftriaxone were effective antibiotics against Escherichia coli, Klebsiella spp., Proteus spp., and Pseudomonas aeruginosa.

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