Abstract

Blood stream infections (BSIs) are one of the most common healthcare-associated infections and are associated with significant morbidity and mortality. Numerous bacteria have been associated with causation of Blood Stream Infections including Gram-negative bacteria and Gram-positive bacteria. He present study was undertaken to know the bacteriological etiology of BSIs and the antibiotic susceptibility pattern of the isolated strains in patients attending to Guntur Government Hospital Guntur, and study was performed in Department of Microbiology Guntur Medical College Guntur. Methods: Retrospective observational study was conducted in Department of Microbiology Guntur Medical college, Guntur to know the bacteriological etiology of BSIs and the antibiotic susceptibility pattern of the isolated strains. RESULTS: Out of the 2133 total cultures 422 (19.78%) were culture positive. Gram positive organisms were MRSA, MSSA, CONS and Enterococci and the Gram negative organisms were K. pneumoniae, K. oxytoca, Pseudomonas, E. coli, Citrobacter and Acinetobacter isolated. AST report showed gram positive bacteria were sensitive to vancomycin and Linezolid. Gram negative bacteria were sensitive to Piperacillin and tazobactam and Imipenem. CONCLUSION: Regular surveillance and isolation of causative agents of BSI’s and their antibiogram should be done in the hospital regularly to decrease the morbidity and mortality

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