Abstract

Nosocomial infection (NI) is the one which usually comes in notice after 48 hours of hospital admission. This study includes bloodstream nosocomial infection. Incidence of nosocomial infections in previous studies were 6-8%. Aim And Objectives: To study bloodstream nosocomial infection and its antibiotics sensitivity and resistance pattern in Paediatrics Intensive Care Unit (PICU). To find out the common organisms leading to bloodstream nosocomial infection and assess the mortality in patients affected by organisms. Material and Methods: This is an observational study conducted in PICU of tertiary care centre. After ethical clearance and proper consent from parents of patients of age of >1 month and <18 years with complain of fever after 48 hour of hospitalization or with new onset of symptom for a period of 1 year (1 Aug 2021-31 July 2022). All patients qualifying the study criteria during data collection period were included in the study (n=86). Blood culture samples were taken for the patients who developed signs of nosocomial infection after 48 hours of hospital admission. Results: The most common organism isolated from blood culture is gram negative bacteria Klebsiella pneumoniae. The sensitivity is observed with carbapenums, fluoroquinolones, polymixins and sulfonamide group of drugs. The resistance pattern of organisms isolated with maximum resistance to cephalosporin, macrolides, glycopeptide and tetracycline group of drugs.

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