Journal of Cardiovascular Disease Research
BIOCHEMICAL EVALUTION OF PATIENTS WITH POLYCYSTIC OVARIAN SYNDROME
Dr. Manojit Chatterjee, Dr. Saptarshi Chakraborty
JCDR. 2021: 3204-3211
Abstract
Introduction: The Polycystic ovary syndrome (PCOS) is considered as a common disturbance of sexual hormonal system. The diagnosis of PCOS is based h/o chronic anovulation, hyperandrogenism and by ultrasonography. PCOS is the major cause of female infertility which increases the risk of development of metabolic syndrome, diabetes mellitus, cardiovascular diseases and some cancer. The studies conducted in the past has proven the association between hyperinsulinemia and development of PCOD. The insulin resistance in PCOS was higher in obese women without PCOS and is a common feature of PCOS in both normal and obese women. Aim and Objectives: To estimate and compare the levels of testosterone, insulin, LDL cholesterol and HbA1c in patients with and without PCOD and to estimate and compare ovarian volume in patients with and without PCOD. Materials and Methods: Detailed history regarding clinical symptoms of PCOs including irregular menstrual cycles and hirsutism, signs of hyperandrogenism and a constellation of oligomenorrhea, amenorrhea, or infertility were recorded. BMI was measured by noting the weight in kgs and height in metre square. After taking informed consent all the patients were subjected to transabdominal and transvaginal ultrasound examination.
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