Abstract

COVID-19 is a newly emerged virus that leads to severe consequences; hence a collaborative approach to COVID-19-positive pregnant women is required. Identifying clinical features of SARS-CoV-2 infection in pregnant women is important as early as possible to decrease it and lower mortality and morbidity associated with it. We have evaluated maternal parameters associated with COVID-19 pregnancy and their clinical outcomes. Obstetric outcomes were compared with the severity of the disease. Material and methods- The study was a single-centred analysis of 71 pregnant women prospectively from April 2021-July 2021. All pregnant patients admitted to our hospital as COVID suspects were recruited. Data collected includes age, parity, gestational age, mode of delivery, comorbidity, haematological parameters, and complications during antenatal periods. Results- Out of 71 cases, the majority, 59(83.1%) cases were symptomatic and 12(16.9%) cases were asymptomatic. According to SPO2 level out of 71 cases, 19(26.8%) cases had severe disease, 36(50.7%) had moderate, 10(14.1%) had mild disease and 6(8.5%) had normal. Maternal mortality was observed 29(40.8%). The mortality rate was higher among 14(48.3%) severe cases and 11(37.9) moderate cases. Serum ferritin was significantly associated with the maternal outcome severity. Conclusion- Mortality was higher in patients with lower levels of spo2, accounting for 48.3%. In these pregnant women, we found a more elevated serum ferritin level, denoting a positive correlation of these biochemical markers with the severity of COVID-19, resulting in adverse maternal outcomes. As limited studies were found on the correlation between biochemical markers and the negative effects in COVID-19 pregnant females, this study can help advance the research further.

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