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Journal of Cardiovascular Disease Research

2021, Vol: 8, Issue: 8
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    Biphasic inhibition of Carrageenan-Induced Paw Edema Model in Rats by Curcuma longa Extract


    Dr N.Nagamani, Dr G Francis Britto, Dr K.R.Subash, Dr S.Kirubakaran raj, Dr Arbind Kumar Choudhary
    JCDR. 2024: 1435-1443

    Abstract

    This study aimed to investigate the anti-inflammatory activity of Curcuma longa (turmeric) alcoholic extract in a carrageenan-induced paw edema model in rats. Materials and Methods: The alcoholic extract of C. longa was prepared and subjected to phytochemical screening and acute oral toxicity studies. The anti-inflammatory activity was evaluated using the carrageenan-induced paw edema model in rats. Animals were administered with the extract (200 mg/kg body weight) or vehicle control one hour before carrageenan injection. Paw edema was measured at various time intervals, and the percentage inhibition of edema was calculated.

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    Volume 15 Issue 3

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