Abstract

Post-operative sore throat (POST) is highly common with the incidence rate as high as 21%–71.8%. The present study was conducted to assess compare the effects of inhaled budesonide suspension, administered using a metered dose inhaler, on occurrence of POST in surgical patients following endotracheal intubation. Materials & Methods: 90 patients of either gender with American society of Anaesthesiologists (ASA) physical status I–II scheduled for short elective laparoscopic surgeries under general anaesthesia with endotracheal intubation were divided 2 groups of 45 each. Group I received 200 µg budesonide inhalation suspension, using a metered dose inhaler, 10 min before intubation, and repeated 6 hours after extubation. In group II, no such intervention was performed. The incidence and severity of POST was recorded. Results: There were 28 males and 17 females in group I and 25 males and 20 females in group II. ASA grade I was 30 in group I and 31 in group II and grade II in 15 in group I and 14 in group II. Mallampatti score 1 was seen in 35 and 32 and 2 in 10 and 13 in group I and II respectively. Number of attempts at intubation was 1 in 36 and 37 and 2 seen among 9 and 8. Rescue therapy for POST was seen among 8 and 25 in group I and II respectively. The difference was significant (P< 0.05). POST at 2 hours, 6 hours, 12 hours and 24 hours was seen in 25% and 70%, 12% and 65%, 6% and 62% and 2% and 58% in group I and II respectively. The difference was significant (P< 0.05). Conclusion: Inhaled budesonide suspension is effective and efficient in reducing the incidence and severity of POST significantly.

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