Abstract

Cirrhosis of liver is a chronic illness, it affects all over body hence it may be considered as a systemic disease. Cardiac involvement diastolic dysfunction, prolong QT interval is common and underdiagnosed in cirrhosis. The aim is to assess the cardiac systolic and diastolic dysfunctions in alcoholic and non-alcoholic cirrhosis patients and controls and compare the cardiac functional status between alcoholic and non - alcoholic cirrhosis patients. Material and methods: The study was conducted in department of gastroenterology at JLN medical college and hospital Ajmer. A total 100 newly diagnosed patients of cirrhosis of liver were selected based on inclusion and exclusion criteria. Alcoholic cirrhosis was present in 40 patients. Age and sex matched 40 healthy subjects without any history of cardiac and liver disease selected as a control. Results: Our study showed statically significantly increased in the ejection fraction in cirrhosis patients compare to controls, A significant increase in PASP was seen in cirrhotics compared to controls in study. Prevalence of diastolic dysfunction in this study in cirrhotic patients was significantly high compared to controls. Conclusions: Cirrhotic patient’s higher occurrence of diastolic dysfunction irrespective of etiology. PASP and EF was significantly higher in cirrhotic patients compare to controls. QTc interval prolongation significantly high in cirrhotic patients and also significantly high in alcoholic cirrhosis compare to non alcoholic cirrhosis patients.

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