ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    Cardiovascular dysfunction in individuals with end-stage liver disease: prevalence and effects on prognosis


    Dr. Ankit Borasi, Dr. Reena Singh, Dr. Ankit Patidar, Dr. Ajay Jain
    JCDR. 2023: 638-642

    Abstract

    Background: The prevalence of cirrhotic cardiomyopathy cannot be determined without diagnostic parameters. Its estimation is a challenging job because the disease is typically latent and only manifests when the patient experiences overt stress, such as changes in body position, exercise, drugs, hemorrhage, or surgery. The goal of this research is to evaluate cardiac dysfunction in patients with end-stage liver disease, examine the relationship between cardiac dysfunction and clinical outcomes in liver disease patients, and investigate the prevalence and effects of cardiac dysfunction. Results: The patients' group had a higher prevalence of diastolic impairment (p<0.001). Only one patient (5.2%) did not have any systolic dysfunction, while nine patients (47.3%) had grade 1 dysfunction, six (31.5%) had grade 2, and three (15.7%) had grade 3 dysfunction. When compared to controls, the patient group's QTc gap was significantly prolonged (p 0.001). Three months of follow-up were given to every subject. Of the 30 patients, 11 passed away during this time. The majority of patients suffer from cardiac failure, primarily diastolic dysfunction. Due to its early onset, diastolic dysfunction has been shown to be the most sensitive measure in the diagnosis of cirrhotic cardiomyopathy. No relationship between cardiac dysfunction and the severity of hepatic sickness was discovered, but the outcome is more affected by the severity of hepatic illness than cardiac dysfunction.

    Description

    » PDF

    Volume & Issue

    Volume 14 Issue 4

    Keywords