ISSN 0975-3583
 

Journal of Cardiovascular Disease Research



    CEFTRIAXONE BLOCKS THE POLYMERIZATION OF Α‑SYNUCLEIN AND EXERTS NEUROPROTECTIVE EFFECTS IN VITRO


    ANCHURI NAGARAJU
    JCDR. 2020: 57-67

    Abstract

    The β-lactam antibiotic ceftriaxone was suggested as a therapeutic agent in several neurodegenerative disorders, either for its ability to counteract glutamate-mediated toxicity, as in cerebral ischemia, or for its ability to enhance the degradation of misfolded proteins, as in Alexander’s disease.

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    Volume & Issue

    Volume 11 Issue 11

    Keywords