Abstract

Abnormalities of the adrenal gland include primary neoplasm, metastases, hemorrhage, or enlargement of the adrenal gland from external hormonal stimulation. Adrenal masses can be divided into two physiologic categories based on whether they hypersecrete a hormone. Hyperfunctioning adrenal masses produce a hormone that results in a chemical imbalance and include pheochromocytomas, aldosteronomas, and cortisol or androgen-producing tumors. Aim & Objective:1. Characterization of adrenal masses using contrast enhanced CT scan. Methods: Study design: Prospective Observational study. Study setting: Department of Radio-diagnosis, Study population: Patients with adrenal masses, measuring more than 1cm, with Hounsfield Unit more than 10. Sample size: 50. Results: The pathological diagnosis was 25 adenomas and 29 non adenomas. Absolute percent washout diagnosed 24 of 25 adenomas and 27 of 29 non adenomas. It had a Sensitivity of 96.00%, Specificity of 93.10%, Positive Predictive Value of 92.31% and Negative Predictive Value of 96.43%. Relative percent washout diagnosed 23 of 25 adenomas and 26 of 29 non adenomas. It had a sensitivity of 92%, specificity of 89.66%, Positive Predictive value of 88.46% and Negative Predictive Value of 92.86%. Both were found to be statistically significant. Conclusions: CT contrast washout study is helpful in categorising adenomas and non-adenomas in adrenal masses with high degree of accuracy, sensitivity and specificity and helps guide clinical management

Description