Journal of Cardiovascular Disease Research
Clinical Evaluation of Laryngopharyngeal Reflux and Its Response to Anti-Reflux Therapy
Dr. Panchanan Sahoo, Dr. Subhalaxmi Rautray, Dr. Monalisa Patsani, Dr. Gaveshani Mantri, Dr. Subrat Kumar Behera
JCDR. 2023: 347-356
Abstract
Laryngopharyngeal reflux disease (LPRD) is a very common presenting condition in otorhinolaryngology departments nowadays, it is very important to diagnose promptly and treat these patients efficiently. The aim of our study is to evaluate symptoms of LPR, laryngeal endoscopic findings, and treatment outcomes of anti-reflux therapy. Methods: This was a prospective study carried out from February 2018 to November 2019. A total number of 140 patients, aged 8 to 65 years, with symptoms of LPR, Reflux Symptom Index (RSI) of more than 13, and Reflux Finding Score (RFS) of more than 7, were included in this study. Result: After recommending dietary and lifestyle changes to all patients, Rabeprazole 20 mg tablets were administered twice daily orally for three months. In our study, it has been seen that there is a significant improvement in RSI and RFS scores after 12 weeks of Proton Pump Inhibitor therapy. Conclusion: We conclude that a combination of RSI and RFS are very useful method in diagnosing LPR patients, treating with twice daily dose of PPI for a duration of 12 weeks shows significant improvement in both symptoms and endoscopic findings of LPR
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