Abstract

The literature data is scarce concerning the immediate and short-term outcomes of pulmonary thromboembolism. However, the long-term outcomes have been well described in the literature Aim: The present study was done to assess the clinical profile and immediate and short-term outcomes in subjects with intermediate-risk pulmonary thromboembolism. The study also evaluated the advantage of thrombolysis in normotensive subjects of pulmonary thromboembolism. Methods: The study assessed subjects having acute and intermediate pulmonary thromboembolism. For all subjects, echocardiography and electrocardiography were done at the time of admission, during stay, discharge, and at follow-up visits. The subjects were managed with anticoagulants or thrombolysis based the hemodynamic decompensation. At the follow-up visits, subjects were assessed for pulmonary arterial hypertension and right ventricular function as echo parameters. Results: In 110 assessed subjects, 52 subjects showed intermediate low-risk PTE (pulmonary thromboembolism) and 58 subjects had intermediate high-risk PTE. The study subjects had sPESI (simplified pulmonary embolism severity index) scores of,2 and were normotensive. In the majority of the subjects, the ECG pattern showed S1Q3T3 with raised levels of cardiac troponin. Subjects managed with thrombolytic agents depicted reduced hemodynamic decompensation compared to subjects with anticoagulants where subjects had clinical features of right heart failure on follow-up at 3 months. Conclusion: The present study adds to the existing literature data concerning the outcomes of intermediate-risk pulmonary thromboembolism and the thrombolysis effects on subjects with hemodynamic stability. The study concluded that the incidence and progression of right heart failure were lesser in subjects with hemodynamic instability

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