Abstract

Conducted a study to know the demographic, clinical and biochemical profile of scrub typhus patients. Material and Method: This prospective, cross sectional study was conducted in the Department of General Medicine at Maharishi Markandeshwar Medical College and Hospital, Kumarhatti, Solan and included 50 cases patients with scrub typhus. The detailed clinical history in which particulars of the patient, chief complaints, history of present illness, past history and family history was taken and physical examination was recorded. Their Complete blood counts, liver function test, kidney function test and serum albumin were done and analysed to find the relation with investigations, symptoms and outcomes of the patient. Results: The majority of patients presented with scrub typhus belonged to 41-50 years age group, with a sex ratio of 1:1. Major presenting symptom was fever, rest of the symptoms were generalized, eschar was present in only one fourth of the patients, hence the diagnosis cannot be ruled out in the absence of eschar. Transaminitis and thrombocytopenia were important investigation finding present in more than three fourth of the patients. Acute hepatitis, AKI, pneumonitis were important complications which lead to MODS. Conclusion: Presence of transaminitis, hypoalbuminemia, thrombocytopenia, AKI, and MODS was associated with poorer outcomes and mortality.

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