Abstract

Ropivacaine is less lipophilic than bupivacaine and that, together with its stereoselective properties, contributes to ropivacaine having a significantly higher threshold for cardiotoxicity and CNS toxicity than bupivacaine in animals, and healthy volunteers. A minimum of 60 patients admitted to Hospital, satisfying the inclusion and exclusion criteria undergoing elective upper limb surgery were included in the study, after obtaining the ethical committee clearance. A prospective study was conducted in patients of either sex requiring elective upper limb surgeries after obtaining an informed consent. There was no statistically significant difference in mean SBP between both the groups at baseline (p=0.823), 5 minutes (p=0.748), 10 minutes (p=0.695), 30 minutes (p=0.068), 45 minutes (p=0.095), 60 minutes (p=0.113), 90 minutes (p=0.071), 180 minutes (p=0.253) and thereafter. There was a statistically significant difference at 15 minutes (p=0.039), 75 minutes (p=0.045), 105 minutes (p=0.040) and at 120 minutes (p=0.036) during follow up. Dexmedetomidine group had lower systolic BP compared to the control group

Description