Abstract

Background Dry eye syndrome (DES) is a common condition characterized by insufficient tear production or excessive tear evaporation, leading to discomfort, visual disturbances, and potential damage to the ocular surface. Carboxy methyl cellulose (CMC) is frequently used in artificial tears for its viscosity and lubricating properties. The addition of glycerin and balanced electrolytes to CMC formulations may enhance moisture retention and support ocular surface health, potentially offering superior relief from DES symptoms. Materials and Methods This study is a randomized, double-blind, controlled trial comparing the efficacy of CMC with glycerin and balanced electrolytes (Group A) versus plain CMC (Group B) in maintaining ocular moisture and alleviating DES symptoms. A total of 100 participants, aged 18-65, were randomized into two groups. The primary outcome was the improvement in Ocular Surface Disease Index (OSDI) scores over eight weeks. Secondary outcomes included changes in tear break-up time (TBUT), Schirmer test results, and patient-reported comfort and satisfaction. Adverse events were also monitored.

Description