Abstract

The pain is the worst symptom experienced by the patient after surgery. Most commonly prescribed analgesic nowadays are nonsteroidal anti-inflammatory drugs (NSAIDs). In this study we compare the analgesic efficacy, side effects and time of rescue analgesia of different routes of Diclofenac administration for postoperative pain relief in lower limb orthopedic surgeries. Methods-The 141 participants of ASA grade 1&II with age group 20-60 yrs of either sex were randomly allocated in 3 groups of 47 each. Patients were induced in subarachnoid block. Transdermal diclofenac patch was applied in group A two hours before the beginnings of surgery; IV Diclofenac75mg injection given at the end of surgery in group B and IM Diclofenac 75 mg was given half an hours before the end of surgery in group C patients. Pain was assessed by using VAS at 2, 6, 12 and 24 hours postoperatively. Times of rescue analgesia were observed and statistical analysis done by SPSS 22 software. Results-. VAS scores were comparable in all three groups at 6 hours with no significant difference (p =0.981).Duration of rescue analgesia was higher in group A as compared to group B and C.(p-0.017) Conclusion–Transdermal diclofenac patch 100 mg has shown better efficacy in comparison to injection diclofenac75 mg given by IM and IV route in providing postoperative analgesia with minimal side effects in lower limb orthopedic surgery under subarachnoid block. Injection diclofenac given by IM route and IV route has shown equivalent efficacy when compared with each other.

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