Abstract

Diabetes mellitus and heart failure are common comorbidities, and their prevalence has increased significantly. Present study was aimed to compare clinical profile and biochemical parameters of cardiac failure in type 2 diabetic vs. non-diabetic patients at a tertiary hospital. Material and Methods: Present study was hospital based, observational, analytical study, conducted in patients of age 18-70 years, either gender, with heart failure clinically selected by using Framingham’s criteria, with type 2 diabetes & other group without diabetes. Results: In present study, 50 patients from each group were studied. Chronic pressure overload is the second most common cause in both groups, comparatively more patients of chronic pressure overload present in non–diabetic group, difference was statistically significant (p- 0.029). Presence of rales was more in diabetic group (68 %) as compared to non-diabetic group (44 %), difference was statistically significant (p- 0.027). In present study, 37 (74%) patients from diabetic group and 21 (42%) patients from non-diabetic group were obese/over-weight, difference was statistically significant (p- 0.002). Arrhythmia, acute myocardial ischemia, mean triglyceride level, Mean cholesterol level in diabetic group was more as compared to non-diabetic group difference was statistically significant. Mean length of hospital stay in diabetic group (6.42 ± 1.939 days) more than from non-diabetic group (4.96 ± 1.261 days), difference was statistically significant (p < 0.001). 8 patients (16%) in diabetic group and 3 patients (6%) in non-diabetic group died & difference was not significant statistically (p > 0.05). Conclusion: Significantly higher numbers of diabetic heart failure patients were obese/overweight, had dyslipidemia andhad deranged renal functions. They had a significantly higher chance of presenting with rales, arrhythmias and acute coronary ischaemia.

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