Abstract

Background There is little literature about the intrathecal use of dexmedetomidine with local anaesthetics in humans. Also, levobupivacaine is known to have lesser CNS and CVS side-effects than its racemic isomer. Fentanyl is a commonly used intrathecal adjuvant. Aims To compare and evaluate the efficacy of levobupivacaine alone, with dexmedetomidine and with fentanyl as adjuvants in spinal anaesthesia for providing adequate analgesia, hemodynamic stability and minimal sedation after infra-umbilical surgeries. Methods A total of 60 patients of ASA I-II of both sexes aged between 20 and 60 years were randomly allocated into three equal groups of 20 patients each. Group L received isobaric levobupivacaine 15 mg with normal saline as control; group LD received levobupivacaine 15 mg with 5 µg dexmedetomidine and group LF received 15 mg of levobupivacaine with 25 mcg of fentanyl, all made up to 4 ml after diluting with normal saline.

Description