Abstract

Lung, oral, oesophageal, stomach and nasopharyngeal cancers are the most common cancers in men, whereas cancers of the breast, cervix and uterus are the most common cancers in women. Although systemic chemotherapy is the most common form of treatment for these cancers, the incidence of surgeries for the same have been on the increasing trend and therefore the need for oncoanesthesia has increased. Methodology- The study was conducted in Department of Anaesthesiology and Pain relief at Kidwai Memorial Institute of Oncology, Bangalore. duration of the study was from November 2019 to November 2021. 210 patients fulfilling the inclusion criteria were included in the study. Patients were divided into 3 groups and randomly allocated to each of them. Designated drug was administered via IV route. Oral intubation with proper cuffed endotracheal tube and its position was confirmed by bilateral five-point auscultation and was connected to volume controlled mode of mechanical ventilation. Monitoring of NIBP, continuous Ecg, Capnography and SpO2 was done. Result- In our study, there was no statistically significant difference in the mean baseline heart rates between the three groups. There is a decrease in mean heart rate after administration of study drug till the time interval before intubation when compared to the baseline heart rate. In our study, there was no statistically significant difference in the mean baseline SBP, DBP and MAP between the three groups. Conclusion- Dexmedetomidine is a better premedication when compared to lignocaine, as it completely attenuated the stress response to intubation

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