Abstract

Few attempts have been made to analyse the relation between blood pressure and serum lipid levels within a population, however, there is no ample data on prevalence of dyslipidemia in hypertensive patient according to Indian hypertensive guideline-IV (2019). This study was therefore undertaken at tertiary care centre for better understanding the lipid profile of hypertensive patient (according to Indian hypertensive guideline-IV-2019) and compare it with normotensive individuals. Methodology-This study was conducted as an observational cross sectional comparative study on hypertensive individuals reporting to Department of Medicine and People’s College of Medical Science and Research Center, Bhopal, during the study period of 18 months. All the cases (hypertensive) and controls (normotensive) were subjected to history taking and detailed clinical examination. All the cases and controls were subjected to lipid profile assessment. Results- This study was conducted on a total of 230 individuals, of them, 115 were hypertensive and remaining 115 were normotensive. We observed no significant difference in age composition and sex between the groups (p>0.05). Mean cholesterol, triglycerides, LDL, VLDL and total cholesterol:HDL ratio was significantly higher in hypertensive group as compared to normotensive group whereas HDL was significantly lower in hypertensive patients (p<0.05). We observed a weak positive correlation of systolic and diastolic blood pressure with cholesterol in hypertensive patients (r=0.326; p<0.05). Conclusions-Hypertension and dyslipidemia are independent risk factors of non-communicable diseases. Hypertension is linked with obesity as well as dyslipidemia. Total cholesterol, triglycerides, LDL, VLDL as well as the ratio of total cholesterol to HDL are significantly higher whereas HDL was significantly lower in hypertensive patients. Thus, hypertension with dyslipidemia may accelerate the atherosclerosis and cardiovascular diseases. As hypertension and dyslipidemia often coexist, lipid profile testing must be indicated in every hypertensive patients and both the conditions must be managed when present together.

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