Abstract

Background: Spine surgeries are performed most often in prone position. The prone position has been pioneered by spine surgeons from the 1930s and 1940s onwards because of the need for better surgical access. Now a day’s spine surgeries are widely performed but excessive blood loss in the field of operation obscures visibility which may lead to increase duration of surgeries and endoscope related complications. In this comparative observational hospital based study, we compare the effect of dexmedetomidine (DEX) and clonidine (CLO) to provide the better surgical field. So, this study was designed to evaluate the effect of dexmedetomidine as hypotensive agent in spine surgeries as compared to clonidine. Materials and Methods: An observational study was conducted in Gandhi Medical College and associated hamidia hospital, Bhopal (MP). The study included 60 ASA I-II patients, age between 20-50 years of either sex undergoing for spine surgeries in routine operation under general anaesthesia (GA) were included in the study. Group 1 (n=30): was given dexmedetomidine 1 μg/kg over 10 minutes,10 minutes before induction of anaesthesia and Group2 (n=30): was given clonidine 1 μg/kg over 10minutes, 10 minutes before induction of anaesthesia. Heart Rate, SBP, MAP, DBP, and Plethysmography (SPO2) were compared for the 2 groups. Data collected were analyzed using SPSS software. Statistical tests employed for the obtained data were chi-square test and unpaired student t-test. Differences were considered statistically significant if P values were <0.05.

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