Abstract

To compare post-operative analgesic efficacy using Bupivacaine Vs Bupivacaine with Magnesium Sulfate in ultra sound guided transversus abdominis plane block in patients undergoing abdominal surgeries. To evaluate the duration of post-operative analgesic efficacy of these drugs; To assess postoperative haemodynamics; Post-operative pain score at 30min, 1hr, 2hr, 3hr, 4hr, 5hr, 6hr, 8hr, 12hr and 24hr; Immediate post-operative complications. Methods: Prospective, randomized, double blinded, comparitive study. The study was conducted in the Department of Anaesthesiology in tertiary care hospital, Vijayawada from May 2022 to Nov 2022, on patients undergoing lower abdominal surgeries. Results: All data were analysed and the demographic profile, duration of surgery and hemodynamic parameters were comparable in both group without any significant difference. The average duration of analgesia was 516 minutes in bupivacaine and Magnesium sulfate group compared to 277 minutes in plain bupivacaine group. Hence duration of analgesia was statistically significant in bupivacaine with Magnesium sulfate group when compared to bupivacaine group. The incidence of complications like post operative nausea, vomiting hypotension and bradycardia was similar in both groups, and it was not statistically significant. Thus the addition of Magnesium sulfate to bupivacine extended the duration of analgesia without any significant side effects in ultrasound guided Transversus abdominis Plane Block. Conclusion: Ultrasound guided Transversus abdominis plane (TAP) block as a technique for providing postoperative analgesia is highly effective for lower abdominal surgeries. The addition of magnesium sulfate to bupivacaine in TAP block extended the duration of analgesia with minimal sedation when compared to plain bupivacaine without significant changes in hemodynamic parameters or complications.

Description