Abstract

For an accurate diagnosis of the breast lump FNAC (Fine Needle Aspiration Cytology) has gained wide popularity and acceptance as a quick, simple and reliable diagnostic procedure that can be carried as outpatient service.5 Present study was aimed to compare diagnostic accuracy of FNAC with histopathology in benign and malignant breast lumps. Material and Methods: Present study was comparative, observational study, conducted in female patients having unknown primary diagnosis of breast lumps and had undergone FNAC followed by excision biopsy/surgery. Results: In present study, 68 female patients having unknown primary diagnosis of breast lumps and had undergone FNAC followed by excision biopsy/surgery. Mean age was 49.5 ± 21.43 years & majority were from <30 years (32.35 %) & 30-39 years (19.12 %). Diagnosis by FNAC was of benign pathology in 46 cases (67.65 %) & malignant in 22 cases (32.35 %). Among benign cases majority were had fibroadenoma (42.65 %) followed by fibrocystic disease (11.76 %), benign cystic lesion (7.35 %) & benign cytological pattern (5.88 %). Among malignant cases majority were had atypical ductal hyperplasia (22.06 %) followed by intraductal carcinoma (5.88 %), ductal hyperplasia without atypia (2.94 %) & phyllodes tumour (1.47 %). When FNAC examination findings were compared with histopathological examinations findings (as standard), sensitivity was 95.45 %, specificity was 97.83 %, positive predictive value was 95.45 %, negative predictive value was 97.83 % & diagnostic accuracy was 94.5 %. Conclusion: Fine needle aspiration cytology is a comfortable, easy, reliable, rapid and simple diagnostic test with sensitivity, specificity, positive predictive value, negative predictive value & diagnostic accuracy of 95.45 %, 97.83 %, 95.45 %, 97.83 % & 94.5 % respectively compared to histopathology as standard.

Description